Aubrey is the most prominent biogerontologist and a "spiritual leader" of the worldwide life extension movement.
He is the Chief Science Officer of SENS Research Foundation, a California-based 501(c)(3) charity dedicated to combating the aging process. Aubrey is also Editor-in-Chief of Rejuvenation Research
, the world's highest-impact peer-reviewed journal focused on intervention in aging. He is a Fellow of both the Gerontological Society of America and the American Aging Association, and sits on the editorial and scientific advisory boards of numerous journals and organisations.
Like many modern gerontologists, Aubrey had begun his career in computer science before switching to biogerontology in the mid-1990s. His research interests encompass the characterisation of all the accumulating and eventually pathogenic molecular and cellular side-effects of metabolism ("damage") that constitute mammalian aging and the design of interventions to repair and/or obviate that damage. He has developed a possibly comprehensive plan for such repair, termed Strategies for Engineered Negligible Senescence
(SENS), which breaks aging down into seven major classes of damage and identifies detailed approaches to addressing each one. A key aspect of SENS is that it can potentially extend healthy lifespan without limit, even though these repair processes will probably never be perfect, as the repair only needs to approach perfection rapidly enough to keep the overall level of damage below pathogenic levels. Aubrey has termed this required rate of improvement of repair therapies "longevity escape velocity".
He describes his approach in detail in his book Ending Aging: The Rejuvenation Breakthroughs That Could Reverse Human Aging in Our Lifetime.
While Aubrey does not subscribe to the programmed theory of aging, he believes that epigenetic rejuvenation can potentially provide us with a meaningful lifespan extension. In his view, the ability to rejuvenate the aged body by reactivating early-life pathways does not in any way conflict with the idea that aging is unprogrammed and results from the gaps in our anti-aging machinery rather than the presence of actively pro-aging machinery.
Aubrey holds a B.A. and a Ph.D. from the University of Cambridge.LinkedIn